Djaman, Joseph Allico and Yapo, Françis Adou and Méité, Souleymane and Mensah-Akaki, Juliana and Bahi, Alexis Gnogbo and Bla, Brice Kouakou (2021) Assessment of Vitamin D Status in Patients Suffering from Uncomplicated Malaria in a Health Center in the District of Abidjan (Côte d’Ivoire). International Journal of Biochemistry Research & Review, 30 (8). pp. 10-17. ISSN 2231-086X
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Abstract
Aims: The pathophysiology of Plasmodium falciparum infection is most often associated with anemia and immune deficiency. Given the important role of vitamin D in the synthesis of hemoglobin and in the stimulation of the immune system, it would be essential to assess the vitamin D status of patients with malaria in order to improve the quality of treatment management.
Methodology: A thick drop and a blood smear were used to determine parasite density and parasite species respectively. The complete blood count was performed using an automated analyzer labelled Sysmex XN 1000i. Biochemical parameters such as calcium and phosphorus were determined using the Cobas C311 Hitachi. The Vidas was used to determine the concentrations of 25 (OH) -vitamin D.
Results: The results showed a decrease in 25 (OH) -vitamin D concentrations in relation to the parasite density and anemia observed in patients with uncomplicated malaria.
Conclusion: Vitamin D status in patients with uncomplicated malaria could represent an essential biomarker in the monitoring of antimalarial treatment.
Item Type: | Article |
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Uncontrolled Keywords: | Plasmodium falciparum; Vitamin D; anemia; Côte d’Ivoire |
Subjects: | Library Eprints > Biological Science |
Depositing User: | Managing Editor |
Date Deposited: | 12 Nov 2022 07:23 |
Last Modified: | 14 Aug 2024 05:25 |
URI: | http://news.pacificarchive.com/id/eprint/107 |