Effect of Supercritical Process Parameters on Phenolic Compound

Carica papaya belonging to the Caricaceae family is an effective medicinal herb that is used as a folk medicine for the treatment of various diseases throughout the world. The present study was designed for evaluation of bioactive compound of dried papaya leaves extract received in supercritical fluid extraction method with special emphasis to the biochemical compound like phenol as well as the effect of various parameters like temperature, pressure, time and particle size on the phenol content. Maximunm phenol amount 1868.25 mg/100 gm was obtained at the at the 70°C and 250 bar pressure and minimum phenol 508.20 mg/100 gm was found at 70°C with 100 bar pressure in the supercritical fluid extraction method.